European Renal Best Practice

European Renal Best Practice - Newsletter #1 November 2012

Please find below the first ERBP newsletter, which brings to your attention new guidance topics provided by European Renal Best Practice, the official guideline organisation of the ERA-EDTA.

These newsletters will be sent to inform you on a regular basis on all ERBP activities and publications. We all hope you enjoy reading this information, and that the provided guidance is of help to you in the daily care for your patients.

If you have comments or suggestions, please do not hesitate to contact us at

Warm regards from the whole ERBP team


Guidance on the treatment of depression in patients with CKD3b-5 or on dialysis now available on the ERBP website

The prevalence of major depression in stage 5 chronic kidney disease (CKD) is high. Patients with CKD who are depressed have a worse quality of life, are hospitalized more often and die sooner than those who are not depressed. Antidepressant drugs are effective in the general population, but whether they improve outcomes in CKD is uncertain. Drug pharmacokinetics are altered in CKD, which may necessitate dose adjustment. This document provides an in-depth review of pharmacokinetics and effectiveness of different ant-depressive medications.

download PDF document

Position statement and update of the KDIGO AKI guidelines now available on the ERBP website

Beginning of 2012, KDIGO presented their guidance on management of AKI, in a very extensive document. Starting from this, ERBP formed two work groups to summarize and update this guideline in a position statement. The first part is now published, and handles diagnosis of AKI (incorporating some new recent insights not yet available at the time the KDIGO AKI guideline was published) and contrast induced nephropathy.

The second part, dealing with renal replacement therapy and anticoagulation, will be published in the near future.

download PDF document

Crush guidelines, available in English, Spanish, Italian, Chinese and Turkish now available on the ERBP website

Crush syndrome is a preventable cause of death after earthquakes. These documents summarize the appropriate therapeutic approach for this not uncommon complication of a fortunately not so frequent event. The recommendations are based on expert judgment and retrospective analyses as no prospective trials have been conducted on treatment of crush victims. However, ERBP believes they provide important guidance, as little people “in the field” have experience in this area, and, by definition, they are only needed under harsh conditions, when there is scarcity of time, means and people. Taking sometimes important under these conditions can be very cumbersome, and therefore, these recommendations on how to manage crush victims are of extreme importance.

The guidance has been produced in collaboration with the RDRTF of ISN, and with Medecins Sans Frontieres (MSF). There is ongoing effort to translate the guidance in even more languages. If you would be tempted or willing to make such a translation in your own language, please do not hesitate to contact us!

Go to ERBP Guideline Publications page for more information

Coming soon: The ERBP guideline on management of donor and recipient of kidney transplant in the peri-operative phase (including preparation and acceptance of living donors)

During the last two years, a team of experts has worked on this guideline, in 4 groups under the supervision of D. Abramowicz. Guidance will be provided on different fields of this topic: how to optimize and handle immunological aspects; donor criteria for living donation; cardiovascular work-up of a transplant recipient; how to deal with acceptors with a history of malignancy or of a disease that potentially recurs after transplantation and so on.

The work of this guideline group is in its final stage, and publication is expected at the end of the year. ERBP will organize a public peer review in the coming weeks, so that you can personally voice your ideas on this new piece of guidance.