European Renal Best Practice
February 27, 2014

Out now!

Guidelines for diagnosing and treating hyponatraemia, a salt imbalance occurring in up to 30% of hospitalised patients, have recently been published simultaneously in three journals: the full guidelines are available online without charge from "Nephrology, Dialysis and Transplantation", the official Journal of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA), from the "European Journal of Endocrinology", the official journal of the European Society of Endocrinology (ESE), and also from "Intensive Care Medicine", the official journal of the European Society of Intensive Care Medicine (ESICM). "This underlines the importance and impact of the guideline, which was developed in collaboration between these three societies", explains Prof. Dr. Raymond Vanholder (Ghent, Belgium), president of the ERA-EDTA. The joint guideline group has conducted a strict systematic literature review with the assistance of the Methodological Support Team of European Renal Best Practice (ERBP), the guidance body of ERA-EDTA, to collect the best available evidence on the diagnosis and management of hypotonic hyponatraemia. The new guidelines were developed on this robust basis of evidence.

The new guidelines advise a pathway for diagnosis which can be conducted in the general hospital setting and focus more closely on the patients' symptoms, giving lower priority to biochemical diagnosis. "That makes them very practice-oriented", emphasises Vanholder. Next to a description of the patho-physiologic basis and a comprehensive rationale of the guidelines, the monograph also contains a number of didactic flow-charts, stepwise depicting the diagnostic and therapeutic interventions, which makes this document extremely suitable at the bedside for the practicing clinician.

Clinical Practice Guideline on Diagnosis and treatment of Hyponatraemia
Nephrol Dial Transplant (2014) 0: 139
doi: 10.1093/ndt/gfu040